Morphology of apoptosis of human hepatocellular carcinoma cell line induced by 2-[(3-carboxy-1-oxoprogy1) amino]-2-deoxy-D-glucose
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منابع مشابه
Antioxidant and Pro-oxidant Effects of Aminoguanidine on HepG-2 Hepatocellular Carcinoma Cell Line
Background and purpose: Hepatocellular carcinoma (HCC) is one of the most fatal cancers, so, proposing new anticancer agents is highly valuable. Production of reactive oxygen species (ROS) is increased in majority of cancers. Increase in ROS leads to cell damage and death. Aminoguanidine (AG) (pimagedine) is one of the compounds that can produce ROS at high concentrations. The present study was...
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Previous studies have shown that DNA cleavage by mammalian topoisomerase II is ATP dependent and can be inhibited by metabolic inhibitors. Furthermore, it has been shown that metabolic inhibitors also have a cytoprotective effect in vitro against topoisomerase II-targeting antitumor drugs. However, the nature of the ATP-dependent process is not known. We have previously shown that doxorubicin i...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2004
ISSN: 2219-2859
DOI: 10.11569/wcjd.v12.i9.2049